Thymalin how Does It Work?
It would appear that people’s overall health is deteriorating, despite the fact that more and more people are becoming aware of the need of maintaining a healthy lifestyle.
The following was discovered in a research published in The Lancet in 2015 that involved 188 nations and over 300 different diseases between the years 1990 and 2013:
In 1990, the number of years of healthy life lost owing to disease accounted for 21 percent of the total; in 2013, that number increased to 31 percent.
33 percent of the population of the globe has 5 health issues or more, whereas just 4 percent of the population reports having NO health problems at all.
Our immune systems have been damaged to the point where they are unable to effectively combat disease. This situation is analogous to the obesity crisis that has befallen the United States, in which people continue to gain weight despite growing awareness of the issue.
As a result, in addition to leading a lifestyle that is completely optimised, we require extra instruments to maintain our immune systems protected and active as we become older.
And one of these instruments happens to be a therapeutic peptide that’s called Thymalin. It’s one of the lesser-known immune-boosting substances in the globe, but it’s a common staple food for the elderly in native Russia.
In this essay, you will learn everything there is to know about the Golden Age agent that your physicians and our healthcare system ought to have been recommending many years ago.
Thymalin is a naturally occurring peptide in your body that is naturally made by your thymus gland. It is also known as Thymic Factor, Thymulin, and Facteur Thymique Serique. Thymalin has a length of 9 amino acids, making it a nonapeptide.
If we were to go through the entire process step by step, beginning to end, you would receive the following:
(It’s worth noting that the distinction between “Thymalin” and “Thymulin” has been the subject of considerable discussion on the internet. Some people use the names interchangeably, while others insist that the two names each represent a different peptide, with one of the peptides consisting of the sequence “H-L-Glu-Trp-OH,” and therefore carry out various functions. Some people use the names interchangeably, while others insist that the two names each represent a different peptide. There is a helpful video on this topic that was created by Jean Francois Tremblay; nonetheless, the word “Thymalin” will continue to be used throughout this page in relation to the peptide that has 9 amino acids.
Although it was isolated and identified in pig blood by a researcher by the name of Jean-Francois Bach in 1977, this particular peptide may be found in the blood of other species of mammalian animals.
It’s possible that you’re asking why the thymus gland is so significant. The thymus gland is the organ that’s principally responsible for your body’s capacity to adjust its immunity:
(If you want an in-depth look into the functions of the thymus gland, reading the paper that I’ve linked to is something that I HIGHLY recommend doing.)
In other words, it helps to differentiate between the chemicals that are naturally produced by our bodies in order to maintain our day-to-day lives and the foreign substances and infections that enter our body.
However, as is the case with everything else in life, the thymus gland shrinks in size and loses its ability to function as one gets older:
Even in the case of healthy ageing, there is a decline in immunological function. The reason for this is that the thymus gland in humans ages more quickly than the rest of the body. It achieves its maximum potential throughout the teenage years, and by the middle years of life, it begins to atrophy, seeing a considerable decline in size as well as function. At the age of 75, the thymus weighs barely one sixth of its maximal weight of 37 grammes when it was younger.
…declining thymus function, along with the glandular atrophy that often accompanies it, is a contributor to greater susceptibility to infection, autoimmune disease, and an increased chance of developing cancer.
The frightening rate at which the thymus gland atrophies is a mystery to us, but academics who study the effects of ageing agree that avoiding thymic atrophy is essential to maintaining good health as one gets older. Therefore, beginning around the age of 35, it is prudent to begin protecting your thymus. And, at the age of 45 to 55, being a really proactive person.”
Because of this, researchers have been looking at peptide bioregulators as a possible means of restoring the function of the thymus gland and extending the period of time during which it may function at its peak.
And despite the fact that thymic peptides like TB-500 and Thymosin Alpha-1 can be useful, the former Soviet Union shifted their emphasis in the 1980s to a different target: thymidine kinase.
“In the 1980s, Slavic investigators, whom we have to thank for the bulk of our knowledge about short peptides, were focused on the options of a thymic peptide bioregulator called thymalin. They discovered that thymalin could spur the thymus to re-grow, thus enhancing immune function. We have to thank these Slavic researchers for the majority of our knowledge about short peptides.
Other desirable anti-aging benefits, such as decreased rates of hypertension and cardiovascular disease, effective organization of metabolism and body weight, improved endocrine health, lower prevalence of acute respiratory illness, lower rates of osteoarthritis and osteoporosis, and rehabilitation of nervous system activity, were also found to result from the use of thymalin.
Although there are no immediate plans to have the FDA approve Thymalin as a medicine, the substance has been in common usage in Russia since the year 2000.
Samson-Med, a pharmaceutical firm with a long history in Russia that was founded in 1937, is the current manufacturer of thymalin.
This brings us to a more significant issue, which is: what role does thymalin play in the functioning of the human body?
When it comes to immunity, the principal method of action of thymalin includes the production of cells that are responsible for generating the immunological response within your body:
T-lymphocytes, which are cells that are engaged in the body’s defence system and are created by the bone marrow, are the primary target of this process since it is primarily intended to generate their development or “education.”
It plays a significant role in the development of these cells from a condition in which they are non-functional to a state in which they are fully functional as defence cells.
After the second year of life, the quantity of thymulin that is generated by the thymus gland begins to decrease, and this trend continues as we get older. Thymulin is one of numerous hormones that are secreted by the thymus gland.
In order to elaborate on this method even further, we may say that thymalin “enhances Th1 cytokine production along with T cell development and maturation, boosting the participation of a particular T helper cell response in antiviral defence” (Source).
In point of fact, this was the major factor that led researchers to explore the peptide as a potential therapy for COVID-19 at an early stage in the pandemic.
